To Study efficacy and safety of citicoline in acute ischemic stroke
نویسندگان
چکیده
منابع مشابه
Edaravone - citicoline comparative study in acute ischemic stroke (ECCS-AIS).
BACKGROUND Two new neuro-protective agents, Edaravone and Citicoline were recently found to be beneficial in acute ischemic stroke (AIS). But there is no study to compare these two agents on same protocol in AIS. This study was aimed to compare these two neuroprotective agents in AIS. METHODS All patients of age more than 18 years who presented within 24 hours of acute ischemic stroke were ra...
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BACKGROUND Pending results from double-blind, multicenter, parallel-group, randomized trials, the benefit and safety of the novel plasminogen activator, desmoteplase remain undetermined. The aim of this meta-analysis was to help evaluate desmoteplase's efficacy and safety. METHODS A thorough search was performed of the Cochrane Library, PubMed, and Embase from the inception of electronic data...
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Background: Thrombolytic therapy is the only approved treatment for acute cerebral ischemia. The hemorrhagic transformation is the greatest complication of this treatment, which may occur after recanalization of occluded artery. The aim of this study was to determine factors associated with clinical improvement and worsening in patients with acute ischemic stroke treated with intravenous th...
متن کاملdysphagia in acute ischemic stroke
Introduction: Swallowing dysfunction complicates acute strokes in 25-32% of cases and directly affects patientschr('39') prognosis and recovery. Dysphagia complicates the course of acute strokes through its potential of the development of chest infection, nutritional problems, and dehydration. Dysphagia is also an independent predictor of respiratory morbidity and mortality in acute stroke. In...
متن کاملA randomized efficacy trial of citicoline in patients with acute ischemic stroke.
BACKGROUND AND PURPOSE Citicoline (cytidine-5'-diphosphocholine; CDP-choline) may reduce central nervous system ischemic injury by stabilizing cell membranes and reducing free radical generation. A previous dose-comparison trial in patients with acute stroke found that 500 mg of citicoline appeared to improve neurological outcome with minimal side effects. METHODS The current trial was a 33-c...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2012
ISSN: 2319-2003
DOI: 10.5455/2319-2003.ijbcp001412